Why do so many promising cancer drugs fail?

We started with a question that has defined our mission: to build a preclinical model that finally reflects human biology.

Our Story

The Question

Why do 97% of oncology drugs fail in clinical trials? This question drove our founding—a frustration shared by scientists watching promising drugs fail in patients. The answer wasn't the drugs. It was the models.

The Breakthrough

Grounded in landmark research, our team developed a method to preserve the entire tumor tissue architecture. The result is not a model of a tumor. It is a living fragment of the patient's tumor.

The Platform

OrgaNova TRiCBiO was founded to translate this breakthrough into a scalable platform. Today, we have a biobank of 1,500+ models and have validated our clinical prediction accuracy at 84.43%.

World-Class Scientists. Industry-Proven Leaders.

Our Journey

2009Foundational Science
2014Oncogenic Transformation

Li, X., Nadauld, L., ..., Kuo, C.J. publish on oncogenic transformation in GI organoids in Nature Medicine (500+ citations).

2016ALI System Published
2018TME Breakthrough
2022Founded
20241,500+ Models
2025US Expansion
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Join Us in Fixing Drug Discovery.