Matched Normal-Tumor Pairs

6 matched normal-tumor pair types in China Biobank. Enables direct comparison of drug effects on tumor vs. normal tissue from the same patient.

PDO 1.0 & 2.0

H&E, IHC, WES (somatic variant calling)

Validated Applications:

  • Therapeutic index / selectivity studies
  • On-target / off-tumor toxicity assessment